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Anti-Human CD70 Rabbit Recombinant Antibody, PBS Only

CD70 Uni-rAbTM Recombinant Antibody for FC
Cat No. 98098-1-PBS
Clone No.241325D8

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

FC

241325D8, CD27 L, CD27 ligand, CD27L, CD27-L

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -


ご購入について

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国内在庫・納期について

約2万点のプロテインテック製品をコスモバイオ社物流センター(国内)に在庫しています。国内在庫の有無はコスモバイオ社ホームページの「品番検索」でカタログ番号を検索して確認できます。


保証・サポートについて

テクニカルサポートまたはご購入後1年間の交換/補填対応を承ります。詳細はこちらをご覧ください。


Tested Applications

Recommended dilution

ApplicationDilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

98098-1-PBS targets CD70 in FC applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen Recombinant Protein 相同性解析による交差性が予測される生物種
Full Name CD70 molecule
Calculated molecular weight 21 kDa
GenBank accession numberBC000725
Gene Symbol CD70
Gene ID (NCBI) 970
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDP32970
Storage Buffer PBS only , pH 7.3
Storage ConditionsStore at -80°C.

Background Information

CD70, also known as tumor necrosis factor ligand superfamily member 7 (TNFSF7) or CD27 ligand (CD27L), is a transmembrane protein that plays a significant role in the immune system. It is the unique ligand for CD27, a member of the tumor necrosis factor receptor (TNFR) family, and is transiently upregulated upon stimulation of immune cells. CD70 is expressed on lymphocytes and dendritic cells, and its expression can be regulated by activation signals received via toll-like receptors (TLRs), CD40, and the antigen receptor MHC II. It provides complex and not completely understood signaling for B cell development. CD70 is also expressed on various solid tumors and hematolymphoid malignancies, where it may contribute to a poor prognosis.

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