CDC25C Monoclonal antibody, PBS Only
CDC25C Monoclonal Antibody for Indirect ELISA, WB
Host / Isotype
Mouse / IgG1
Reactivity
rat, mouse, human
Applications
Indirect ELISA, WB
Conjugate
Unconjugated
CloneNo.
2B6B12
Cat no : 66912-1-PBS
Synonyms
Validation Data Gallery
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
66912-1-PBS targets CDC25C in Indirect ELISA, WB applications and shows reactivity with rat, mouse, human samples.
| Tested Reactivity | rat, mouse, human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | CDC25C fusion protein Ag10240 相同性解析による交差性が予測される生物種 |
| Full Name | cell division cycle 25 homolog C (S. pombe) |
| Calculated molecular weight | 473 aa, 53 kDa |
| Observed molecular weight | 46-53 kDa |
| GenBank accession number | BC019089 |
| Gene symbol | CDC25C |
| Gene ID (NCBI) | 995 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purification |
| Storage Buffer | PBS Only |
| Storage Conditions | Store at -80°C. |
Background Information
The cell division cycle 25 (CDC25) family of proteins are highly conserved dual specificity phosphatases that activate cyclin-dependent kinase (CDK) complexes, which in turn regulate progression through the cell division cycle. CDC25C (cell division cycle 25 homolog C) is one of the 3 isoforms of CDC25 in mammalian cells. It is present in the cytoplasm of asynchronously growing human cells (PMID:10330186). And it may be phosphorylated by its own substrate, an active cdc2-cyclin B complex, to create an autoactivation loop (PMID:7937793). It can be hyperphosphorylated to get the active form of 70 kDa (PMID:18296513). CDC25C has some isofroms with molecular mass of 46-53 kDa.
