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CDC6 Monoclonal antibody, PBS Only

CDC6 Monoclonal Antibody for WB, IF/ICC, Indirect ELISA
Cat No. 66021-1-PBS
Clone No.6F12D2

Host / Isotype

Mouse / IgG1

Reactivity

human, mouse, rat

Applications

WB, IF/ICC, Indirect ELISA

CDC6-related protein, CDC6 related protein, Cdc18-related protein, CDC18L, Cdc18 related protein

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -


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国内在庫・納期について

約2万点のプロテインテック製品をコスモバイオ社物流センター(国内)に在庫しています。国内在庫の有無はコスモバイオ社ホームページの「品番検索」でカタログ番号を検索して確認できます。


保証・サポートについて

テクニカルサポートまたはご購入後1年間の交換/補填対応を承ります。詳細はこちらをご覧ください。


Tested Applications

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

66021-1-PBS targets CDC6 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen CDC6 fusion protein Ag17958 相同性解析による交差性が予測される生物種
Full Name cell division cycle 6 homolog (S. cerevisiae)
Calculated molecular weight 560 aa, 63 kDa
Observed molecular weight 65 kDa
GenBank accession numberBC025232
Gene Symbol CDC6
Gene ID (NCBI) 990
RRIDAB_2881493
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDQ99741
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

CDC6, also named as CDC18L and HsCDC18, belongs to the CDC6/cdc18 family. It is involved in the initiation of DNA replication and functions as a regulator at the early steps of DNA replication. It also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Defects in CDC6 are the cause of Meier-Gorlin syndrome type 5 (MGORS5). MGORS5 is a syndrome characterized by bilateral microtia, aplasia/hypoplasia of the patellae, and severe intrauterine and postnatal growth retardation with short stature and poor weight gain. This antibody is a mouse monoclonal antibody raised against residues near the C terminus of human CDC6.

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