Validation Data Gallery
Tested Applications
Recommended dilution
Application | Dilution |
---|---|
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. |
Product Information
84749-1-PBS targets CDK5 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Reactivity | human, mouse, rat |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Immunogen | CDK5 fusion protein Ag28465 相同性解析による交差性が予測される生物種 |
Full Name | cyclin-dependent kinase 5 |
Calculated molecular weight | 31 kDa, 33 kDa |
Observed molecular weight | 31-33 kDa |
GenBank accession number | BC005115 |
Gene Symbol | CDK5 |
Gene ID (NCBI) | 1020 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purfication |
UNIPROT ID | Q00535 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
Cyclin-dependent kinase 5 (CDK5), belongs to the cyclin-dependent kinase family, is a proline-directed serine/threonine-protein kinase that essential for neuronal cell cycle arrest and differentiation and may be involved in apoptotic cell death in neuronal diseases by triggering abortive cell cycle re-entry. CDK5 predominantly expressed in neurons where it phosphorylates both high molecular weight neurofilaments and microtubule-associated protein tau.