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Target

Host

Species Reactivity

Species Reactivity

Conjugate

Conjugate

CDK5 Recombinant antibody, PBS Only

CDK5 Recombinant Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

241908F10

Cat no : 84749-1-PBS

Synonyms

PSSALRE, EC:2.7.11.1, Cyclin-dependent-like kinase 5, Cyclin-dependent kinase 5, Cdk 5

Validation Data Gallery

Filter:
  • Western Blot (WB) analysis of various lysates using CDK5 Recombinant antibody (84749-1-RR)

    WB analysis using 84749-1-RR (same clone as 84749-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84749-1-RR (CDK5 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84749-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of rat brain tissue using CDK5 Recombinant antibody (84749-1-RR)

    IHC staining of rat brain using 84749-1-RR (same clone as 84749-1-PBS)

    Immunohistochemical analysis of paraffin-embedded rat brain tissue slide using 84749-1-RR (CDK5 antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84749-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of rat brain tissue using CDK5 Recombinant antibody (84749-1-RR)

    IHC staining of rat brain using 84749-1-RR (same clone as 84749-1-PBS)

    Immunohistochemical analysis of paraffin-embedded rat brain tissue slide using 84749-1-RR (CDK5 antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84749-1-PBS in a different storage buffer formulation.

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Tested Applications

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

The immunogen of 84749-1-PBS is CDK5 Fusion Protein expressed in E. coli.

Tested Reactivity human, mouse, rat
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen CDK5 fusion protein Ag28465 相同性解析による交差性が予測される生物種
Full Name cyclin-dependent kinase 5
Calculated molecular weight 31 kDa, 33 kDa
Observed molecular weight 31-33 kDa
GenBank accession numberBC005115
Gene symbol CDK5
Gene ID (NCBI) 1020
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

Cyclin-dependent kinase 5 (CDK5), belongs to the cyclin-dependent kinase family, is a proline-directed serine/threonine-protein kinase that essential for neuronal cell cycle arrest and differentiation and may be involved in apoptotic cell death in neuronal diseases by triggering abortive cell cycle re-entry. CDK5 predominantly expressed in neurons where it phosphorylates both high molecular weight neurofilaments and microtubule-associated protein tau.