p16INK4a Polyclonal antibody
p16INK4a Polyclonal Antibody for WB, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
mouse, rat
Applications
WB, ELISA
Conjugate
Unconjugated
Cat no : 28416-1-AP
Synonyms
Validation Data Gallery
Tested Applications
Positive WB detected in | NIH/3T3 cells, Neuro-2a cells, RAW 264.7 cells, C6 cells, mouse uterus tissue |
Recommended dilution
Application | Dilution |
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Western Blot (WB) | WB : 1:500-1:2000 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
Product Information
28416-1-AP targets p16INK4a in WB, ELISA applications and shows reactivity with mouse, rat samples.
Tested Reactivity | mouse, rat |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | p16INK4a fusion protein Ag28927 相同性解析による交差性が予測される生物種 |
Full Name | cyclin-dependent kinase inhibitor 2A |
Calculated molecular weight | 18 kDa |
Observed molecular weight | 19 kDa |
GenBank accession number | NM_001040654 |
Gene symbol | Cdkn2a |
Gene ID (NCBI) | 12578 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
Cdkn2a (cyclin-dependent kinase inhibitor 2a) is a cell cycle regulating gene encoding alternate proteins, p16Ink4a and p19Arf, that arrest the G1 phase through CDK4/6 inhibition. As they are tumor suppressors, p16Ink4a and p19Arf can be targeted for treatment of various cancers, including melanoma, cervical, and esophageal cancers.
Protocols
Product Specific Protocols | |
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WB protocol for p16INK4a antibody 28416-1-AP | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |