Validation Data Gallery
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Product Information
17941-1-AP targets CLEC4C in ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | CLEC4C fusion protein Ag12363 相同性解析による交差性が予測される生物種 |
| Full Name | C-type lectin domain family 4, member C |
| Calculated molecular weight | 213 aa, 25 kDa |
| GenBank accession number | BC074968 |
| Gene Symbol | CLEC4C |
| Gene ID (NCBI) | 170482 |
| RRID | AB_2878469 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q8WTT0 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
CLEC4C (C-type lectin domain family 4 member C), also known as DLEC, BDCA-2, CD303, and HECL, is a type II membrane protein that contains one C-type lectin domain. The C-type lectin domain family members share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signaling, glycoprotein turnover, and roles in inflammation and immune response. CLEC4C is a specific surface marker of human plasmacytoid dendritic cells, centrally involved in antigen presentation and immune tolerance. (PMID: 15481152; PMID: 15476922; PMID: 34486917; PMID: 23847189)