CLSTN3 Monoclonal antibody, PBS Only (Capture)

CLSTN3 Monoclonal Antibody for Cytometric bead array, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

human

Applications

Cytometric bead array, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

3D4F8

Cat no : 68855-3-PBS

Synonyms

Alc-beta, alcbeta, Alcadein-beta, Alcadein beta, Alc beta


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Tested Applications

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

68855-3-PBS targets CLSTN3 as part of a matched antibody pair:

MP50250-2: 68855-3-PBS capture and 68855-2-PBS detection (validated in Cytometric bead array)

Unconjugated mouse monoclonal antibody pair in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation.

This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.

Tested Reactivity human
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen CLSTN3 fusion protein Ag14897 相同性解析による交差性が予測される生物種
Full Name calsyntenin 3
Calculated molecular weight 968 aa, 107 kDa
GenBank accession numberBC039075
Gene symbol CLSTN3
Gene ID (NCBI) 9746
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G Magarose purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

Calsyntenins, also called alcadeins, are cadherin superfamily proteins first identified as synaptic proteins (PMID: 11161476; 12498782). Calsyntenins are type I transmembrane proteins with extracellular domains containing two cadherin repeats and an LNS (laminin, neurexin, sex hormone-binding globulin) domain (PMID: 24613359). Calsyntenin-3 (CLSTN3, also known as alcadein-beta) is a synapse-organizing protein that promotes the development of synapses. It is a postsynaptic adhesion molecule that binds to presynaptic neurexins to mediate both excitatory and inhibitory synapse formation (PMID: 25352602; 24613359).