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Target

Host

Species Reactivity

Species Reactivity

Conjugate

Conjugate

CLUL1 Polyclonal antibody

CLUL1 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 27498-1-AP

Synonyms

Retinal-specific clusterin-like protein, Clusterin-like protein 1, Clusterin like protein 1, clusterin like 1 (retinal)

Validation Data Gallery

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  • Western Blot (WB) analysis of various lysates using CLUL1 Polyclonal antibody (27498-1-AP)

    WB analysis using 27498-1-AP

    Various lysates were subjected to SDS PAGE followed by western blot with 27498-1-AP (CLUL1 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours.

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Tested Applications

Positive WB detected inARPE-19 cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:1000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

27498-1-AP targets CLUL1 in WB, ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen CLUL1 fusion protein Ag26570 相同性解析による交差性が予測される生物種
Full Name clusterin-like 1 (retinal)
Calculated molecular weight 54 kDa
Observed molecular weight70 kDa
GenBank accession numberBC025381
Gene symbol CLUL1
Gene ID (NCBI) 27098
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

Clusterin-like protein 1 (CLUL1) functions as a molecular chaperone, protecting stressed proteins, and is upregulated in various neurodegenerative conditions, suggesting a role in defense against neuronal damage (PMID: 17148042). It is specifically expressed in cone photoreceptor cells and is regulated by the cone-rod homeobox (CRX) (PMID: 14507903). Mutations of CLUL1 were investigated in the context of age-related macular degeneration (AMD), a leading cause of blindness in the elderly (PMID: 17148042).

Protocols

Product Specific Protocols
WB protocol for CLUL1 antibody 27498-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols