- Featured Product
- KD/KO Validated
CNOT9 Polyclonal antibody, PBS Only
CNOT9 Polyclonal Antibody for WB, IHC, IF/ICC, IP, Indirect ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse, rat
Applications
WB, IHC, IF/ICC, IP, Indirect ELISA
Conjugate
Unconjugated
Cat no : 22503-1-PBS
Synonyms
Validation Data Gallery
Tested Applications
Recommended dilution
Application | Dilution |
---|---|
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. |
Product Information
22503-1-PBS targets CNOT9 in WB, IHC, IF/ICC, IP, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Reactivity | human, mouse, rat |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | CNOT9 fusion protein Ag18197 相同性解析による交差性が予測される生物種 |
Full Name | RCD1 required for cell differentiation1 homolog (S. pombe) |
Calculated molecular weight | 299 aa, 34 kDa |
Observed molecular weight | 30-40 kDa |
GenBank accession number | BC007102 |
Gene symbol | CNOT9 |
Gene ID (NCBI) | 9125 |
RRID | AB_11232413 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
RQCD1, also known as CNOT9, is a highly conserved transcriptional cofactor predominantly expressed in actively diffierentiating tissues like testis and thymus. It is a component of the CCR4-NOT complex, the major effector complex in miRNA-mediated gene silencing. Overexpression of RQCD1 has been reported in serveral tumors, indicating that it may be a potential molecular target for cancer treatment.