Collagen Type VII Polyclonal antibody
Collagen Type VII Polyclonal Antibody for WB, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human
Applications
WB, ELISA
Conjugate
Unconjugated
Cat no : 19799-1-AP
Synonyms
Validation Data Gallery
Tested Applications
Positive WB detected in | HeLa cells |
Recommended dilution
Application | Dilution |
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Western Blot (WB) | WB : 1:500-1:1000 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
Product Information
19799-1-AP targets Collagen Type VII in WB, ELISA applications and shows reactivity with human samples.
Tested Reactivity | human |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | Peptide 相同性解析による交差性が予測される生物種 |
Full Name | collagen, type VII, alpha 1 |
Calculated molecular weight | 295 kDa |
Observed molecular weight | 290 kDa |
GenBank accession number | NM_000094 |
Gene symbol | COL7A1 |
Gene ID (NCBI) | 1294 |
RRID | AB_2878609 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
COL7A1, also named as LC collagen, is a stratified squamous epithelial basement membrane protein that forms anchoring fibrils which may contribute to epithelial basement membrane organization and adherence by interacting with extracellular matrix (ECM) proteins such as type IV collagen. Defects in COL7A1 are the cause of epidermolysis bullosa dystrophica (DEB). Defects in COL7A1 are the cause of epidermolysis bullosa dystrophica Pasini type (P-DEB) which also known as albopapuloid dominant dystrophic epidermolysis bullosa. Defects in COL7A1 are the cause of epidermolysis bullosa dystrophica Hallopeau-Siemens type (HS-DEB). Defects in COL7A1 are the cause of transient bullous dermolysis of the newborn (TBDN). Defects in COL7A1 are the cause of epidermolysis bullosa dystrophica pretibial type (PR-DEB). Defects in COL7A1 are the cause of epidermolysis bullosa dystrophica Bart type (B-DEB). Defects in COL7A1 are the cause of epidermolysis bullosa pruriginosa (EBP). Defects in COL7A1 are the cause of isolated toenail dystrophy without skin fragility. Defects in COL7A1 are the cause of epidermolysis bullosa dystrophica with subcorneal cleavage (EBDSC) which also known as epidermolysis bullosa simplex superficialis (EBSS). This antibody is specific to COL7A1.
Protocols
Product Specific Protocols | |
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WB protocol for Collagen Type VII antibody 19799-1-AP | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |