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  • Featured Product
  • KD/KO Validated

COX7A2L Polyclonal antibody, PBS Only

COX7A2L Polyclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 11416-1-PBS

Synonyms

Validation Data Gallery

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  • Western Blot (WB) analysis of various lysates using COX7A2L Polyclonal antibody (11416-1-AP)

    WB analysis using 11416-1-AP (same clone as 11416-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 11416-1-AP (COX7A2L antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11416-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human ovary tumor tissue using COX7A2L Polyclonal antibody (11416-1-AP)

    IHC staining of human ovary tumor using 11416-1-AP (same clone as 11416-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human ovary tumor using 11416-1-AP (COX7A2L antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 11416-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human ovary tumor tissue using COX7A2L Polyclonal antibody (11416-1-AP)

    IHC staining of human ovary tumor using 11416-1-AP (same clone as 11416-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human ovary tumor using 11416-1-AP (COX7A2L antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 11416-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human ovary tumor tissue using COX7A2L Polyclonal antibody (11416-1-AP)

    IHC staining of human ovary tumor using 11416-1-AP (same clone as 11416-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human ovary tumor using 11416-1-AP (COX7A2L antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 11416-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human ovary tumor tissue using COX7A2L Polyclonal antibody (11416-1-AP)

    IHC staining of human ovary tumor using 11416-1-AP (same clone as 11416-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human ovary tumor using 11416-1-AP (COX7A2L antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 11416-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human breast cancer tissue using COX7A2L Polyclonal antibody (11416-1-AP)

    IHC staining of human breast cancer using 11416-1-AP (same clone as 11416-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer using 11416-1-AP (COX7A2L antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 11416-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human breast cancer tissue using COX7A2L Polyclonal antibody (11416-1-AP)

    IHC staining of human breast cancer using 11416-1-AP (same clone as 11416-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer using 11416-1-AP (COX7A2L antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 11416-1-PBS in a different storage buffer formulation.

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Tested Applications

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

11416-1-PBS targets COX7A2L in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen COX7A2L fusion protein Ag1980 相同性解析による交差性が予測される生物種
Full Name cytochrome c oxidase subunit VIIa polypeptide 2 like
Calculated molecular weight 114 aa, 13 kDa
Observed molecular weight 14 kDa
GenBank accession numberBC007095
Gene symbol COX7A2L
Gene ID (NCBI) 9167
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

Cytochrome c oxidase (COX) is the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. The mitochondrially encoded subunits function in electron transfer, and the nuclear encoded subunits may function in the regulation and assembly of the complex. COX7A2L (cytochrome c oxidase subunit 7A-related protein), also known as COX7AR or COX7RP, is an inner mitochondrial membrane protein. This gene is expressed in all tissues, and upregulated in a breast cancer cell line after estrogen treatment. Recently it was found that DNA methylation of COX7A2L had a significant association with therapy response in patients with breast cancer. In Alzheimer's disease the expression of COX7A2L was reduced.