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Target

Host

Species Reactivity

Species Reactivity

Conjugate

Conjugate

CRLF3 Polyclonal antibody

CRLF3 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 11567-1-AP

Synonyms

CREME 9, CREME9, CRLF3, CYTOR4, FRWS, P48

Validation Data Gallery

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  • Western Blot (WB) analysis of various lysates using CRLF3 Polyclonal antibody (11567-1-AP)

    WB analysis using 11567-1-AP

    U-251 cells were subjected to SDS PAGE followed by western blot with 11567-1-AP (CRLF3 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

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Tested Applications

Positive WB detected inU-251 cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:2000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

11567-1-AP targets CRLF3 in WB, ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen CRLF3 fusion protein Ag2144 相同性解析による交差性が予測される生物種
Full Name cytokine receptor-like factor 3
Calculated molecular weight 442 aa, 50 kDa
Observed molecular weight51 kDa
GenBank accession numberBC023567
Gene symbol CRLF3
Gene ID (NCBI) 51379
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

Cytokine receptor-like factor 3 (CRLF3), a member of the group 1 in the prototypic class I cytokine receptors, contains the conserved cytokine receptor motif WSXWS, a single transmembrane segment and an intracellular Janus kinase (JAK) docking site (PMID: 31680856). CRLF3 is expressed in most normal human tissues and many tumor cell lines and has been reported to negatively regulate cell cycle progression (PMID: 19427400). CRLF3 has been identified as a human neuroprotective EV-3 (Epo) receptor (PMID: 37168680). It is involved neurogenesis, neuron survival, and dendritic development (PMID: 34233200).

Protocols

Product Specific Protocols
WB protocol for CRLF3 antibody 11567-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols