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Species Reactivity
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Species Reactivity
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Conjugate
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Conjugate
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Conjugate
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Target

Host

Species Reactivity

Species Reactivity

Conjugate

Conjugate

CTHRC1 Recombinant antibody

CTHRC1 Recombinant Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

Human

Applications

WB, ELISA

Conjugate

Unconjugated

CloneNo.

240442E1

Cat no : 83629-1-RR

Synonyms

UNQ762/PRO1550, Protein NMTC1, Collagen triple helix repeat-containing protein 1, collagen triple helix repeat containing 1, 240442E1

Validation Data Gallery

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  • Western Blot (WB) analysis of A375 cells using CTHRC1 Recombinant antibody (83629-1-RR)

    WB analysis of A375 using 83629-1-RR

    A375 cells were subjected to SDS PAGE followed by western blot with 83629-1-RR (CTHRC1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours.

  • Affinity experiments of 83629-1-RR

    Affinity experiments of 83629-1-RR

    Biolayer interferometry (BLl) kinetic assays of 83629-1-RR against Human CTHRC1 were performed. The affinity constant is 72.9 pM.

Tested Applications

Positive WB detected inA375 cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:5000-1:50000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

The immunogen of 83629-1-RR is CTHRC1 Fusion Protein expressed in E. coli.

Tested Reactivity Human
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen CTHRC1 fusion protein Ag9812 相同性解析による交差性が予測される生物種
Full Name collagen triple helix repeat containing 1
Calculated molecular weight 243 aa, 26 kDa
Observed molecular weight 25 kDa
GenBank accession numberBC014245
Gene symbol CTHRC1
Gene ID (NCBI) 115908
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

Collagen triple helix repeat-containing protein 1 (CTHRC1), also known as protein NMTC1, is a glycosylated secreted protein. CTHRC1 was identified as a novel molecular in injured and diseased arteries where it may contribute to vascular remodeling by limiting collagen matrix deposition and promoting cell migration (PMID: 15618538). It has been reported that CTHRC1 is a positive regulator of osteoblastic bone formation (PMID: 18779865). Besides, studies reveal that CTHRC1 expression is implicated in various malignancies, including hepatocellular carcinoma, gastric carcinoma, colon cancer, and lung cancer (PMID: 23922981; 24504172; 24746208; 25139095).

Protocols

Product Specific Protocols
WB protocol for CTHRC1 antibody 83629-1-RRDownload protocol
Standard Protocols
Click here to view our Standard Protocols