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Caspase 1 Recombinant antibody, PBS Only

Caspase 1 Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA
Cat No. 81482-1-PBS
Clone No.1O18

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

CASP1, Caspase1, Caspase-1, CASP-1, CASP 1

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -


ご購入について

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国内在庫・納期について

約2万点のプロテインテック製品をコスモバイオ社物流センター(国内)に在庫しています。国内在庫の有無はコスモバイオ社ホームページの「品番検索」でカタログ番号を検索して確認できます。


保証・サポートについて

テクニカルサポートまたはご購入後1年間の交換/補填対応を承ります。詳細はこちらをご覧ください。


Tested Applications

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

81482-1-PBS targets Caspase 1 in WB, Indirect ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen Caspase 1 fusion protein Ag11143 相同性解析による交差性が予測される生物種
Full Name caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)
Calculated molecular weight 404 aa, 45 kDa
Observed molecular weight30 kDa, 35 kDa, 43-45 kDa
GenBank accession numberBC062327
Gene Symbol Caspase 1
Gene ID (NCBI) 834
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP29466
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

CASP1(caspase-1) is also named as IL1BC, IL1BCE and belongs to the peptidase C14A family. It is a cysteine protease that regulates inflammatory processes through its capacity to process and activate the interleukin-1-beta (IL1B), IL18, and IL33 precursor proteins. The active caspase-1 can increase cellular membrane permeability and intracellular calcium levels, which facilitates lysosome exocytosis and release of host antimicrobial factors and microbial products (PMID:21804020). It has 5 isoforms produced by alternative splicing. 81482-1-RR can recognize the splicing isoforms of caspase 1.

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