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Cyclin D3 Monoclonal antibody, PBS Only

Cyclin D3 Monoclonal Antibody for WB, IHC, ELISA
Cat No. 66357-1-PBS
Clone No.1F2C6

Host / Isotype

Mouse / IgG1

Reactivity

human

Applications

WB, IHC, ELISA

CCND3, cyclin D, Cyclin D3, G1/S specific cyclin D3

Formulation:  PBS and Azide
PBS and Azide
Conjugate:  Unconjugated
Size/Concentration: 

-/ -


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保証・サポートについて

テクニカルサポートまたはご購入後1年間の交換/補填対応を承ります。詳細はこちらをご覧ください。


Tested Applications

66357-1-Ig

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

66357-1-PBS targets Cyclin D3 in WB, IHC, ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen Cyclin D3 fusion protein Ag22825 相同性解析による交差性が予測される生物種
Full Name cyclin D3
Calculated molecular weight 33 kDa
Observed molecular weight 33-35 kDa
GenBank accession numberBC011616
Gene Symbol Cyclin D3
Gene ID (NCBI) 896
ENSEMBL Gene IDENSG00000112576
RRIDAB_2881736
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP30281
Storage Buffer PBS only
Storage ConditionsStore at -80°C.

Background Information

Cyclin D3 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activitiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation.

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