Validation Data Gallery
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Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
12094-1-PBS targets DDIT4L in WB, Indirect ELISA applications and shows reactivity with mouse samples.
| Tested Reactivity | mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | DDIT4L fusion protein Ag2735 相同性解析による交差性が予測される生物種 |
| Full Name | DNA-damage-inducible transcript 4-like |
| Calculated molecular weight | 193 aa, 22 kDa |
| Observed molecular weight | 22 kDa |
| GenBank accession number | BC013592 |
| Gene Symbol | DDIT4L |
| Gene ID (NCBI) | 115265 |
| RRID | AB_2918027 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q96D03 |
| Storage Buffer | PBS only , pH 7.3 |
| Storage Conditions | Store at -80°C. |
Background Information
DNA-damage-inducible transcript 4-like protein(DDIT4L), encoded by the stress responsive gene REDD2, is a negative regulator of mTOR signaling, and expressed predominantly in skeletal muscle. It regulates the TOR signaling pathway upstream of the TSC1-TSC2 complex and downstream of AKT1. Also, DDIT4L involves in oxidized low-density lipoprotein-induced macrophage death sensitivity.