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- KD/KO Validated
DLGAP3 Polyclonal antibody
DLGAP3 Polyclonal Antibody for WB, IHC, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse and More (1)
Applications
WB, IHC, IF, ELISA
Conjugate
Unconjugated
Cat no : 55056-1-AP
Synonyms
Validation Data Gallery
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Tested Applications
| Positive WB detected in | human brain tissue, mouse brain tissue |
| Positive IHC detected in | human stomach tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:500-1:1000 |
| Immunohistochemistry (IHC) | IHC : 1:50-1:500 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Published Applications
| KD/KO | See 1 publications below |
| WB | See 3 publications below |
| IF | See 1 publications below |
Product Information
55056-1-AP targets DLGAP3 in WB, IHC, IF, ELISA applications and shows reactivity with human, mouse samples.
| Tested Reactivity | human, mouse |
| Cited Reactivity | human, mouse, rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide 相同性解析による交差性が予測される生物種 |
| Full Name | discs, large (Drosophila) homolog-associated protein 3 |
| Calculated molecular weight | 106 kDa |
| Observed molecular weight | 106-120 kDa |
| GenBank accession number | NM_001080418 |
| Gene symbol | DLGAP3 |
| Gene ID (NCBI) | 58512 |
| RRID | AB_10858793 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
DLGAP3, also named as DAP3, belongs to the SAPAP family. It may play a role in the molecular organization of synapses and neuronal cell signaling. DLGAP3 could be an adapter protein linking ion channel to the subsynaptic cytoskeleton. It may induce enrichment of PSD-95/SAP90 at the plasma membrane. The antibody has no cross reaction to other DLGAP members.
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for DLGAP3 antibody 55056-1-AP | Download protocol |
| IHC protocol for DLGAP3 antibody 55056-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
Publications
| Species | Application | Title |
|---|---|---|
Biol Psychiatry Metabotropic Glutamate Receptor and Fragile X Signaling in a Female Model of Escalated Aggression. | ||
Cell Death Dis SAPAP3 regulates epileptic seizures involving GluN2A in post-synaptic densities.
| ||
Nat Neurosci Neuronal activity rapidly reprograms dendritic translation via eIF4G2:uORF binding |
