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Target

Host

Species Reactivity

Species Reactivity

Conjugate

Conjugate

DRD4 Polyclonal antibody

DRD4 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

Human, Pig, mouse and More (1)

Applications

WB, IF, ELISA

Conjugate

Unconjugated

Cat no : 28094-1-AP

Synonyms

D(2C) dopamine receptor, D(4) dopamine receptor, D4DR, Dopamine D4 receptor, dopamine receptor D4, DRD4

Validation Data Gallery

Filter:
  • Western Blot (WB) analysis of mouse brain tissue using DRD4 Polyclonal antibody (28094-1-AP)

    WB analysis of mouse brain using 28094-1-AP

    mouse brain tissue were subjected to SDS PAGE followed by western blot with 28094-1-AP (DRD4 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

  • Western Blot (WB) analysis of pig brain tissue using DRD4 Polyclonal antibody (28094-1-AP)

    WB analysis of pig brain using 28094-1-AP

    pig brain tissue were subjected to SDS PAGE followed by western blot with 28094-1-AP (DRD4 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

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Tested Applications

Positive WB detected inmouse brain tissue, pig brain tissue

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:200-1:1000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Published Applications

IFSee 1 publications below

Product Information

28094-1-AP targets DRD4 in WB, IF, ELISA applications and shows reactivity with Human, Pig, mouse samples.

Tested Reactivity Human, Pig, mouse
Cited Reactivityrat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen DRD4 fusion protein Ag26930 相同性解析による交差性が予測される生物種
Full Name dopamine receptor D4
Calculated molecular weight 44 kDa
Observed molecular weight 40-44 kDa
GenBank accession numberNM_000797
Gene symbol DRD4
Gene ID (NCBI) 1815
RRIDAB_2881058
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

The family of dopamine receptors (DRs) includes five G protein-coupled receptors (GPCRs)-DRD1, DRD2, DRD3, DRD4 and DRD5-with different anatomical distribution, expression levels, dopamine affinity, signal transduction, and effector targets (PMID:36523297). DRD4 (dopamine receptor D4) influences the postsynaptic action of dopamine and is implicated in many neurological processes, exhibits polymorphism and is one of the most studied genes in connection with psychiatric disorders (PMID:21873960). Moreover, DRD4 modulate glucose metabolism, and protect neurocytes from anoxia/reoxygenation (A/R) injury. Thus, DRD4 might regulate myocardial I/R injury in association with GLUT4-mediated glucose metabolism (PMID:33584304).

Protocols

Product Specific Protocols
WB protocol for DRD4 antibody 28094-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
ratIF

Aging (Albany NY)

Sepsis induced cognitive impairments by disrupting hippocampal parvalbumin interneuron-mediated inhibitory network via a D4-receptor mechanism.

Authors - Muhuo Ji
View Article