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Target

Host

Species Reactivity

Species Reactivity

Conjugate

Conjugate

Desmocollin 2 Monoclonal antibody, PBS Only

Desmocollin 2 Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG2a

Reactivity

human, mouse

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

1H8G1

Cat no : 60239-1-PBS

Synonyms

ARVD11, Cadherin family member 2, CDHF2, desmocoilin, desmocollin 2, Desmocollin 3, Desmosomal glycoprotein II, Desmosomal glycoprotein III, DG2, DGII/III, DSC2, DSC3

Validation Data Gallery

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  • Western Blot (WB) analysis of HEK-293 cells using Desmocollin 2 Monoclonal antibody (60239-1-Ig)

    WB analysis of HEK-293 using 60239-1-Ig (same clone as 60239-1-PBS)

    HEK-293 cells were subjected to SDS PAGE followed by western blot with 60239-1-Ig (Desmocollin 2 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60239-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of Raji cells using Desmocollin 2 Monoclonal antibody (60239-1-Ig)

    WB analysis of Raji using 60239-1-Ig (same clone as 60239-1-PBS)

    Raji cells were subjected to SDS PAGE followed by western blot with 60239-1-Ig (Desmocollin 2 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60239-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of HEK-293 cells using Desmocollin 2 Monoclonal antibody (60239-1-Ig)

    WB analysis of HEK-293 using 60239-1-Ig (same clone as 60239-1-PBS)

    HEK-293 cells were subjected to SDS PAGE followed by western blot with 60239-1-Ig (Desmocollin 2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60239-1-PBS in a different storage buffer formulation.

Tested Applications

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

60239-1-PBS targets Desmocollin 2 in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Immunogen Desmocollin 2 fusion protein Ag5450 相同性解析による交差性が予測される生物種
Full Name desmocollin 2
Calculated molecular weight 100 kDa
Observed molecular weight 110 kDa
GenBank accession numberBC063291
Gene symbol DSC2
Gene ID (NCBI) 1824
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

Desmocollin 2 (DSC2) is a member of the desmocollin subfamily of the cadherin superfamily. The desmocollins (DSC1-3), along with the desmogleins (DSG1-4), are found primarily in epithelia and cardiac muscle where they constitute the adhesive proteins of the intercellular desmosome junctions and are required for cell adhesion and desmosome formation. Mutations in DSC2 gene are associated with arrhythmogenic right ventricular dysplasia-11.