Validation Data Gallery
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Tested Applications
| Positive WB detected in | human placenta tissue |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:1000-1:4000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Published Applications
| WB | See 3 publications below |
Product Information
67008-1-Ig targets Endothelin 1 in WB, ELISA applications and shows reactivity with Human samples.
| Tested Reactivity | Human |
| Cited Reactivity | human, mouse |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | Endothelin 1 fusion protein Ag28334 相同性解析による交差性が予測される生物種 |
| Full Name | endothelin 1 |
| Calculated molecular weight | 212 aa, 24 kDa |
| Observed molecular weight | 24 kDa |
| GenBank accession number | BC009720 |
| Gene Symbol | Endothelin 1 |
| Gene ID (NCBI) | 1906 |
| RRID | AB_2882325 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein G purification |
| UNIPROT ID | P05305 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| Storage Conditions | Store at -20°C. Aliquoting is unnecessary for -20oC storage. |
Background Information
EDN1, also named as Endothelin-1, PPET1 and ET-1, belongs to the endothelin/sarafotoxin family. Endothelins are endothelium-derived vasoconstrictor peptides. Emerging basic science, and animal and human data all suggest that EDN1 is a potentially important contributor in the pathobiology of fibrosing disorders, including those that affect the lung(PMID:20055532 ).
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for Endothelin 1 antibody 67008-1-Ig | Download protocol |
| FC protocol for Endothelin 1 antibody 67008-1-Ig | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
Publications
| Species | Application | Title |
|---|---|---|
J Trace Elem Med Biol The association between endothelial function and autoimmune thyroiditis induced by iodine excess | ||
Biomed Rep Cilostazol regulates the expressions of endothelin-1 and endothelial nitric oxide synthase via activation of the p38 MAPK signaling pathway in HUVECs | ||
Hypertens Res Endothelial-derived complement factor D contributes to endothelial dysfunction in malignant nephrosclerosis via local complement activation |