Validation Data Gallery
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Tested Applications
| Positive IHC detected in | human colon tissue, human liver tissue, mouse testis tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
Recommended dilution
| Application | Dilution |
|---|---|
| Immunohistochemistry (IHC) | IHC : 1:50-1:500 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Published Applications
| WB | See 1 publications below |
Product Information
17276-1-AP targets EFCAB1 in WB, IHC, ELISA applications and shows reactivity with human, mouse samples.
| Tested Reactivity | human, mouse |
| Cited Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | EFCAB1 fusion protein Ag11039 相同性解析による交差性が予測される生物種 |
| Full Name | EF-hand calcium binding domain 1 |
| Calculated molecular weight | 211 aa, 24 kDa |
| GenBank accession number | BC025676 |
| Gene Symbol | EFCAB1 |
| Gene ID (NCBI) | 79645 |
| RRID | AB_2878375 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q9HAE3 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
EFCAB1, also known as Calaxin, is a gene that encodes a protein involved in the function of cilia and flagella, which are hair-like structures protruding from the surface of certain cells. Research indicates that EFCAB1 overexpression inhibits cell proliferation, migration, and invasion while promoting apoptosis in lung adenocarcinoma cells. This suggests that EFCAB1 could potentially serve as a biomarker for lung adenocarcinoma.
Protocols
| Product Specific Protocols | |
|---|---|
| IHC protocol for EFCAB1 antibody 17276-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
Publications
| Species | Application | Title |
|---|---|---|
Andrology A novel homozygous LRRC6 mutation causes male infertility with asthenozoospermia and primary ciliary dyskinesia in humans |