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- KD/KO Validated
EGFL7 Polyclonal antibody
EGFL7 Polyclonal Antibody for ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human and More (2)
Applications
WB, IF, IHC, ELISA
Conjugate
Unconjugated
Cat no : 19291-1-AP
Synonyms
Validation Data Gallery
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Published Applications
| KD/KO | See 2 publications below |
| WB | See 11 publications below |
| IHC | See 4 publications below |
| IF | See 1 publications below |
Product Information
The immunogen of 19291-1-AP is EGFL7 Fusion Protein expressed in E. coli.
| Tested Reactivity | human |
| Cited Reactivity | human, rat, mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | EGFL7 fusion protein Ag6559 相同性解析による交差性が予測される生物種 |
| Full Name | EGF-like-domain, multiple 7 |
| Calculated molecular weight | 273 aa, 30 kDa |
| GenBank accession number | BC012377 |
| Gene symbol | EGFL7 |
| Gene ID (NCBI) | 51162 |
| RRID | AB_10643993 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
Epidermal growth factor-like domain-containing protein 7 (EGFL7), also known as vascular endothelial statin, is an endothelial cell-derived secreted factor that regulates vascular tube formation. This protein may be involved in the growth and proliferation of tumor cells. Recent studies have reported elevated expression of EGFL7 in several tumors and cancer cell lines, including kidney tumors, malignant gliomas, hepatocellular carcinomas, and colon cancers.
Protocols
| Product Specific Protocols | |
|---|---|
| IHC protocol for EGFL7 antibody 19291-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
Publications
| Species | Application | Title |
|---|---|---|
Blood Adv The EGFL7-ITGB3-KLF2 axis enhances survival of multiple myeloma in preclinical models.
| ||
Mol Ther Nucleic Acids Role of ANKHD1/LINC00346/ZNF655 Feedback Loop in Regulating the Glioma Angiogenesis via Staufen1-Mediated mRNA Decay. | ||
Sci China Life Sci Role of EGFL7/EGFR-signaling pathway in migration and invasion of growth hormone-producing pituitary adenomas. | ||
Hum Gene Ther Attenuation of EGFL7 expression inhibits growth hormone-producing pituitary adenomas growth and invasion. | ||
Tumour Biol EGFL7 participates in regulating biological behavior of growth hormone-secreting pituitary adenomas via Notch2/DLL3 signaling pathway. |
