ENO1 Monoclonal antibody, PBS Only
ENO1 Monoclonal Antibody for WB, IF/ICC, Indirect ELISA
Host / Isotype
Mouse / IgM
Reactivity
human, mouse, rat, pig
Applications
WB, IF/ICC, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
1D6E8
Cat no : 67187-1-PBS
Synonyms
Validation Data Gallery
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
67187-1-PBS targets ENO1 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse, rat, pig samples.
| Tested Reactivity | human, mouse, rat, pig |
| Host / Isotype | Mouse / IgM |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | ENO1 fusion protein Ag17518 相同性解析による交差性が予測される生物種 |
| Full Name | enolase 1, (alpha) |
| Calculated molecular weight | 47 kDa |
| Observed molecular weight | 47 kDa |
| GenBank accession number | BC015641 |
| Gene symbol | ENO1 |
| Gene ID (NCBI) | 2023 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Thiophilic affinity chromatograph |
| Storage Buffer | PBS Only |
| Storage Conditions | Store at -80°C. |
Background Information
ENO1, also named as NNE, ENO1L1, MBPB1, MPB1 and MBP1, belongs to the enolase family. ENO1 is a metabolic enzyme involved in the synthesis of pyruvate. It also acts as a plasminogen receptor and mediates the activation of plasmin and extracellular matrix degradation. In tumor cells, ENO1 is up-regulated and supports the Warburg effect; it is expressed at the cell surface, where it promotes cancer invasion, and is subjected to a specific array of post-translational modifications, namely acetylation, methylation and phosphorylation. ENO1 overexpression and post-translational modifications could be of diagnostic and prognostic value in many cancer types. (PMID: 27814656)
