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Target

Host

Species Reactivity

Species Reactivity

Conjugate

Conjugate

ERCC6/CSB Polyclonal antibody

ERCC6/CSB Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 20548-1-AP

Synonyms

ARMD5, ATP dependent helicase ERCC6, CKN2, Cockayne syndrome protein CSB, COFS, COFS1, CSB, ERCC6, RAD26

Validation Data Gallery

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  • Western Blot (WB) analysis of mouse brain tissue using ERCC6/CSB Polyclonal antibody (20548-1-AP)

    WB analysis of mouse brain using 20548-1-AP

    mouse brain tissue were subjected to SDS PAGE followed by western blot with 20548-1-AP (ERCC6/CSB antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

  • Western Blot (WB) analysis of mouse brain tissue using ERCC6/CSB Polyclonal antibody (20548-1-AP)

    WB analysis of mouse brain using 20548-1-AP

    mouse brain tissue were subjected to SDS PAGE followed by western blot with 20548-1-AP (ERCC6/CSB antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

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Tested Applications

Positive WB detected inmouse brain tissue

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:200-1:1000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

20548-1-AP targets ERCC6/CSB in WB, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Peptide 相同性解析による交差性が予測される生物種
Full Name excision repair cross-complementing rodent repair deficiency, complementation group 6
Calculated molecular weight 168 kDa
Observed molecular weight 150 kDa
GenBank accession numberNM_000124
Gene symbol ERCC6/CSB
Gene ID (NCBI) 2074
RRIDAB_10732961
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

ERCC6, also named as CSB, belongs to the SNF2/RAD54 helicase family. It is involved in the preferential repair of active genes. It is presumed DNA or RNA unwinding function. ERCC6 corrects the UV survival and RNA synthesis after UV exposure of Cockayne syndrome complementation group B. Defects in ERCC6 are the cause of Cockayne syndrome type B (CSB) , cerebro-oculo-facio-skeletal syndrome type 1 (COFS1), De Sanctis-Cacchione syndrome (DSC), and UV-sensitive syndrome (UVS). Genetic variation in ERCC6 is associated with susceptibility to age-related macular degeneration type 5 (ARMD5). The antibody is specific to ERCC6.

Protocols

Product Specific Protocols
WB protocol for ERCC6/CSB antibody 20548-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols