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ETV6 Monoclonal antibody, PBS Only

ETV6 Monoclonal Antibody for WB, IHC, ELISA
Cat No. 67579-1-PBS
Clone No.2A5A2

Host / Isotype

Mouse / IgG1

Reactivity

Human

Applications

WB, IHC, ELISA

ETS related protein Tel1, ETS translocation variant 6, ets variant 6, ETV6, TEL, TEL/ABL, TEL1, Transcription factor ETV6

Formulation:  PBS and Azide
PBS and Azide
Conjugate:  Unconjugated
Size/Concentration: 

-/ -


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国内在庫・納期について

約2万点のプロテインテック製品をコスモバイオ社物流センター(国内)に在庫しています。国内在庫の有無はコスモバイオ社ホームページの「品番検索」でカタログ番号を検索して確認できます。


保証・サポートについて

テクニカルサポートまたはご購入後1年間の交換/補填対応を承ります。詳細はこちらをご覧ください。


Tested Applications

67579-1-Ig

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

67579-1-PBS targets ETV6 in WB, IHC, ELISA applications and shows reactivity with Human samples.

Tested Reactivity Human
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen ETV6 fusion protein Ag30054 相同性解析による交差性が予測される生物種
Full Name ets variant 6
Calculated molecular weight 452 aa, 53 kDa
Observed molecular weight60 kDa
GenBank accession numberBC043399
Gene Symbol ETV6
Gene ID (NCBI) 2120
RRIDAB_2918493
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP41212
Storage Buffer PBS only
Storage ConditionsStore at -80°C.

Background Information

ETV6(ETS Variant Transcription Factor 6), also known as TEL, is a Protein Coding gene. ETV6 is a member of the ETS family of transcription factors encoded by the ETS variant 6 gene (ETV6), located on chromosome 12p13.2. ETV6 protein contains 3 domains: a) the pointed N-terminal (i.e. PNT) domain which forms oligomer partners with itself as well as other transcription factors (e.g. FLI1) and is required for ETV6's transcriptional repressing activity; b) the central regulatory domain; and c) the C-terminal DNA-binding domain(PMID: 22578774). ETV6 is highly expressed in early hematopoietic progenitor cells(HPCs) and is essential for hematopoiesis in the bone marrow(PMID: 31248877).

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