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  • KD/KO Validated

FAH Polyclonal antibody

FAH Polyclonal Antibody for WB, ELISA
Cat No. 14928-1-AP

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IF, ELISA

Beta diketonase, FAA, FAH, Fumarylacetoacetase, Fumarylacetoacetate hydrolase

Formulation:  PBS and Azide
PBS and Azide
Conjugate:  Unconjugated
Unconjugated
Size/Concentration: 

-/ -


ご購入について

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国内在庫・納期について

約2万点のプロテインテック製品をコスモバイオ社物流センター(国内)に在庫しています。国内在庫の有無はコスモバイオ社ホームページの「品番検索」でカタログ番号を検索して確認できます。


保証・サポートについて

テクニカルサポートまたはご購入後1年間の交換/補填対応を承ります。詳細はこちらをご覧ください。


Tested Applications

Positive WB detected inmouse liver tissue, rat liver tissue

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:2000-1:10000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

14928-1-AP targets FAH in WB, IF, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen FAH fusion protein Ag6704 相同性解析による交差性が予測される生物種
Full Name fumarylacetoacetate hydrolase (fumarylacetoacetase)
Calculated molecular weight 46 kDa
Observed molecular weight 40-45 kDa
GenBank accession numberBC002527
Gene Symbol FAH
Gene ID (NCBI) 2184
RRIDAB_2246738
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDP16930
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

FAH is also named as FAA(fumarylacetoacetase), the last enzyme in tyrosine degradation, functionally important in the liver and kidney(PMID:8473520). FAH is a metabolic enzyme catalyzing the last step of tyrosine and phenylalanine catabolism: the hydrolysis of fumarylacetoacetate into acetoacetate and fumarate. In humans, deficiency of this activity is associated with the metabolic disease hereditary tyrosinaemia type I, which is also known as hepatorenal tyrosinaemia(PMID:17768357).

Protocols

Product Specific Protocols
WB protocol for FAH antibody 14928-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanWB

Int J Cancer

Protein predictive signatures for lymph node metastasis of gastric cancer.

Authors - Li Wei W

Am J Pathol

Protein Profiling of H. pylori-Associated Gastric Cancer.

Authors - Guodong Lian

PLoS One

Protein Profiling of Bladder Urothelial Cell Carcinoma.

Authors - Jinghai Hu

Int J Oncol

PMID: 29393385

Authors - Guodong Lian

Oncol Rep

The screening and analysis of protein signatures and signaling associated with chemoresistance based on Protein Pathway Array technology in gastric cancer.

Authors - Guodong Lian
humanWB

Cartilage

Low-Frequency Vibration Promotes Tumor Necrosis Factor-α Production to Increase Cartilage Degeneration in Knee Osteoarthritis.

Authors - Peng-Ming Yu
  • KD Validated
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