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Species Reactivity
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Conjugate
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Conjugate
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Conjugate
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Target

Host

Species Reactivity

Species Reactivity

Conjugate

Conjugate

FDPS Monoclonal antibody, PBS Only

FDPS Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG2b

Reactivity

Human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

3B8A7

Cat no : 67972-1-PBS

Synonyms

FDPS, FPP synthase, FPPS, FPS, KIAA1293

Validation Data Gallery

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  • Western Blot (WB) analysis of various lysates using FDPS Monoclonal antibody (67972-1-Ig)

    WB analysis using 67972-1-Ig (same clone as 67972-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67972-1-Ig (FDPS antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. The membrane was stripped and reblotted with HRP-conjugated Alpha Tubulin Monoclonal antibody (HRP-66031) as loading control. This data was developed using the same antibody clone with 67972-1-PBS in a different storage buffer formulation.

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Tested Applications

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

67972-1-PBS targets FDPS in WB, Indirect ELISA applications and shows reactivity with Human samples.

Tested Reactivity Human
Host / Isotype Mouse / IgG2b
Class Monoclonal
Type Antibody
Immunogen FDPS fusion protein Ag9247 相同性解析による交差性が予測される生物種
Full Name farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase)
Calculated molecular weight 419 aa, 48 kDa
Observed molecular weight38-39 kDa
GenBank accession numberBC010004
Gene symbol FDPS
Gene ID (NCBI) 2224
RRIDAB_2918722
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

FPPS (also known as FDPS) is a key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites including sterols, dolichols, carotenoids, and ubiquinones. The expression of FPPS was elevated in prostate tumor cell lines, indicating its potential role in prostate cancer progression.