Validation Data Gallery
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Tested Applications
| Positive WB detected in | K-562 cells, A549 cells, Jurkat cells, HeLa cells, HEK-293 cells |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:5000-1:50000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Product Information
83296-4-RR targets FGD6 in WB, ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Immunogen | FGD6 fusion protein Ag22211 相同性解析による交差性が予測される生物種 |
| Full Name | FYVE, RhoGEF and PH domain containing 6 |
| Calculated molecular weight | 1430 aa, 161 kDa |
| Observed molecular weight | 161 kDa |
| GenBank accession number | BC013319 |
| Gene Symbol | FGD6 |
| Gene ID (NCBI) | 55785 |
| RRID | AB_3670963 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purfication |
| UNIPROT ID | Q6ZV73 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
FGD6, also known as ZFYVE24, is localized on the Homo sapiens chromosome 12q22 and consists of 1,400 amino acids. Previous studies have reported that variations in FGD6 increase individual susceptibility to polypoidal choroidal vasculopathy. It was also demonstrated that FGD6 coordinates cell polarity and endosomal membrane recycling in osteoclasts by regulating the assembly of different actin-based protein networks and activating Cdc42 at different locations.
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for FGD6 antibody 83296-4-RR | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |