FGF18 Monoclonal antibody
FGF18 Monoclonal Antibody for WB, ELISA
Host / Isotype
Mouse / IgG2a
Reactivity
human, mouse, rabbit
Applications
WB, ELISA
Conjugate
Unconjugated
CloneNo.
1D11D12
Cat no : 60341-1-Ig
Synonyms
Validation Data Gallery
Tested Applications
| Positive WB detected in | HT-1080 cells, NIH/3T3 cells |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:500-1:2000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Published Applications
| WB | See 1 publications below |
Product Information
60341-1-Ig targets FGF18 in WB, ELISA applications and shows reactivity with human, mouse, rabbit samples.
| Tested Reactivity | human, mouse, rabbit |
| Cited Reactivity | human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | FGF18 fusion protein Ag2041 相同性解析による交差性が予測される生物種 |
| Full Name | fibroblast growth factor 18 |
| Calculated molecular weight | 207 aa, 24 kDa |
| Observed molecular weight | 21 kDa |
| GenBank accession number | BC006245 |
| Gene symbol | FGF18 |
| Gene ID (NCBI) | 8817 |
| RRID | AB_2881450 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purification |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
FGF18 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. It has been shown in vitro that this protein is able to induce neurite outgrowth in PC12 cells. Studies of the similar proteins in mouse and chick suggested that this protein is a pleiotropic growth factor that stimulates proliferation in a number of tissues, most notably the liver and small intestine. Knockout studies of the similar gene in mice implied the role of this protein in regulating proliferation and differentiation of midline cerebellar structures.
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for FGF18 antibody 60341-1-Ig | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
Publications
| Species | Application | Title |
|---|---|---|
J Exp Clin Cancer Res HDAC7 promotes NSCLC proliferation and metastasis via stabilization by deubiquitinase USP10 and activation of β-catenin-FGF18 pathway. |
