Validation Data Gallery
Tested Applications
Positive WB detected in | Jurkat cells, NIH/3T3 cells, HEK-293 cells |
Recommended dilution
Application | Dilution |
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Western Blot (WB) | WB : 1:200-1:1000 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
Product Information
23257-1-AP targets FIZ1 in WB, ELISA applications and shows reactivity with human, mouse samples.
Tested Reactivity | human, mouse |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | FIZ1 fusion protein Ag19760 相同性解析による交差性が予測される生物種 |
Full Name | FLT3-interacting zinc finger 1 |
Calculated molecular weight | 496 aa, 52 kDa |
Observed molecular weight | 52 kDa |
GenBank accession number | BC136512 |
Gene Symbol | FIZ1 |
Gene ID (NCBI) | 84922 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
UNIPROT ID | Q96SL8 |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
FLT3 interacting zinc finger 1 (FIZ1) is a ubiquitous expressed protein that composes of 11 C2H2 zinc finger domains spread over the entire protein in clusters of two, three, or four fingers. The interaction of FIZ1 was mapped to the catalytic domain of FLT3, which is a receptor tyrosine kinase involved in proliferation and survival of hematopoietic progenitor cells as well as differentiation of early B lymphoid progenitors (10409713). In the mammalian retina, FIZ1 interacts with NRL (Neural-Retina Leucine-zipper), an essential transcriptional activator of rod photoreceptor-specific genes, and the concentration of FIZ1 in the retina will increase during photoreceptor terminal maturation (18854042).
Protocols
Product Specific Protocols | |
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WB protocol for FIZ1 antibody 23257-1-AP | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |