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  • KD/KO Validated

FKBP1A Polyclonal antibody

FKBP1A Polyclonal Antibody for WB, IHC, ELISA
Cat No. 10273-1-AP

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat and More (1)

Applications

WB, IHC, ELISA

FKBP12, FKBP1, FKBP 1A, FK506-binding protein 1A, Calstabin-1

Formulation:  PBS and Azide
PBS and Azide
Conjugate:  Unconjugated
Unconjugated
Size/Concentration: 

-/ -


ご購入について

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国内在庫・納期について

約2万点のプロテインテック製品をコスモバイオ社物流センター(国内)に在庫しています。国内在庫の有無はコスモバイオ社ホームページの「品番検索」でカタログ番号を検索して確認できます。


保証・サポートについて

テクニカルサポートまたはご購入後1年間の交換/補填対応を承ります。詳細はこちらをご覧ください。


Tested Applications

Positive WB detected inmouse brain tissue, Jurkat cells, rat brain tissue
Positive IHC detected inhuman normal colon
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:2000
Immunohistochemistry (IHC)IHC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

10273-1-AP targets FKBP1A in WB, IHC, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivityhuman, mouse, pig
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen FKBP1A fusion protein Ag0406 相同性解析による交差性が予測される生物種
Full Name FK506 binding protein 1A, 12kDa
Calculated molecular weight 12 kDa
Observed molecular weight 12 kDa
GenBank accession numberBC001925
Gene Symbol FKBP1A
Gene ID (NCBI) 2280
RRIDAB_2231588
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDP62942
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

FKBP1A(FK506-binding protein 1A) is also named as FKBP1, FKBP12 and belongs to the FKBP-type PPIase family.It keeps in an inactive conformation TGFBR1, the TGF-beta type I serine/threonine kinase receptor, preventing TGF-beta receptor activation in absence of ligand and catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

Protocols

Product Specific Protocols
WB protocol for FKBP1A antibody 10273-1-APDownload protocol
IHC protocol for FKBP1A antibody 10273-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanWB

Cell Rep

Sequencing of captive target transcripts identifies the network of regulated genes and functions of primate-specific miR-522.

Authors - Shen Mynn Tan
pigWB

Food Chem

TMT-based quantitative proteomic analysis of porcine muscle associated with postmortem meat quality.

Authors - Xinhua Hou
humanWB

Oncotarget

TGFBR-IDH1-Cav1 axis promotes TGF-β signalling in cancer-associated fibroblast.

Authors - Xiaodan Hou
humanWB

Mol Pharmacol

FK506 Binding Protein 12 Modulates μ Opioid Receptor Phosphorylation and PKC{epsilon}-dependent Signaling by its Direct Interaction with the Receptor.

Authors - Qiu Yu Y
  • KD Validated
mouseWB

Development

PFN4 is required for manchette development and acrosome biogenesis during mouse spermiogenesis

Authors - Naila Umer
humanWB

Int J Med Sci

Integrated analysis of FKBP1A/SLC3A2 axis in everolimus inducing ferroptosis of breast cancer and anti-proliferation of T lymphocyte

Authors - Zihan Chen
  • KD Validated
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