Validation Data Gallery
Tested Applications
Recommended dilution
Application | Dilution |
---|---|
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. |
Product Information
66548-1-PBS targets FMR1 in Indirect ELISA, IP, IHC, WB applications and shows reactivity with rat, mouse, human samples.
Tested Reactivity | rat, mouse, human |
Host / Isotype | Mouse / IgG2a |
Class | Monoclonal |
Type | Antibody |
Immunogen | FMR1 fusion protein Ag4697 相同性解析による交差性が予測される生物種 |
Full Name | fragile X mental retardation 1 |
Calculated molecular weight | 632 aa, 71 kDa |
Observed molecular weight | 69-72 kDa |
GenBank accession number | BC038998 |
Gene Symbol | FMR1 |
Gene ID (NCBI) | 2332 |
RRID | AB_2881910 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | Q06787 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
The selective RNA-binding protein FMRP forms a messenger ribonucleoprotein complex that associates with polyribosomes, implicating in regulation of translation. FMR1 is a component of the CYFIP1-EIF4E-FMR1 complex which binds to and reperss the mRNA. It also has a role in the transport of mRNA from the nucleus to the cytoplasm. FMR1 exists several isforms and the molecular weight of FMR1 is about 59-72 kDa.