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Target

Host

Species Reactivity

Species Reactivity

Conjugate

Conjugate

Toca 1 Polyclonal antibody

Toca 1 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 55055-1-AP

Synonyms

C1orf39, FNBP1L, formin binding protein 1 like, Toca 1, TOCA1

Validation Data Gallery

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  • Western Blot (WB) analysis of mouse brain tissue using Toca 1 Polyclonal antibody (55055-1-AP)

    WB analysis of mouse brain using 55055-1-AP

    mouse brain tissue were subjected to SDS PAGE followed by western blot with 55055-1-AP (Toca 1 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

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Tested Applications

Positive WB detected inmouse brain tissue

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:1000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

55055-1-AP targets Toca 1 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Peptide 相同性解析による交差性が予測される生物種
Full Name formin binding protein 1-like
Calculated molecular weight 70 kDa
Observed molecular weight 63-75 kDa
GenBank accession numberNM_017737
Gene symbol Toca 1
Gene ID (NCBI) 54874
RRIDAB_10858792
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Aliquoting is unnecessary for -20oC storage.

Background Information

Toca-1, also named as FNBP1L or C1orf39, belongs to the FNBP1 family. It is required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. Toca-1 may bind to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promote membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by activating the WASL/N-WASP-WASPIP/WIP complex, the predominant form of WASL/N-WASP in cells. The antibody is specific to Toca-1.

Protocols

Product Specific Protocols
WB protocol for Toca 1 antibody 55055-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols