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FNTB Monoclonal antibody, PBS Only

FNTB Monoclonal Antibody for WB, IF/ICC, FC (Intra), ELISA

Host / Isotype

Mouse / IgG1

Reactivity

human, mouse

Applications

WB, IF/ICC, FC (Intra), ELISA

Conjugate

Unconjugated

CloneNo.

1F3B10

Cat no : 66783-1-PBS

Synonyms

FTase-beta, FTase beta, FPTB, EC:2.5.1.58, 1F3B10


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Tested Applications

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

66783-1-PBS targets FNTB in WB, IF/ICC, FC (Intra), ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen FNTB fusion protein Ag27796 相同性解析による交差性が予測される生物種
Full Name farnesyltransferase, CAAX box, beta
Calculated molecular weight 437 aa, 49 kDa
Observed molecular weight 44-45 kDa
GenBank accession numberBC020232
Gene symbol FNTB
Gene ID (NCBI) 2342
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

FNTB is the catalytic β subunit of farnesyltransferase which is an alpha/beta heterodimeric enzyme attaching a farnesyl group to a single cysteine in several cellular proteins like RAS and facilitating their translocation from the cytoplasm to the plasma membrane. Farnesyltransferase inhibitors have been developed as ant-tumor agents. FNTB is required for the homeostasis of skin keratinocytes.