Validation Data Gallery
Tested Applications
Recommended dilution
Application | Dilution |
---|---|
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. |
Product Information
66783-1-PBS targets FNTB in WB, IF/ICC, FC (Intra), ELISA applications and shows reactivity with human, mouse samples.
Tested Reactivity | human, mouse |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Immunogen | FNTB fusion protein Ag27796 相同性解析による交差性が予測される生物種 |
Full Name | farnesyltransferase, CAAX box, beta |
Calculated molecular weight | 437 aa, 49 kDa |
Observed molecular weight | 44-45 kDa |
GenBank accession number | BC020232 |
Gene Symbol | FNTB |
Gene ID (NCBI) | 2342 |
RRID | AB_2882128 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | P49356 |
Storage Buffer | PBS only |
Storage Conditions | Store at -80°C. |
Background Information
FNTB is the catalytic β subunit of farnesyltransferase which is an alpha/beta heterodimeric enzyme attaching a farnesyl group to a single cysteine in several cellular proteins like RAS and facilitating their translocation from the cytoplasm to the plasma membrane. Farnesyltransferase inhibitors have been developed as ant-tumor agents. FNTB is required for the homeostasis of skin keratinocytes.