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  • Featured Product
  • KD/KO Validated

FOXC1 Monoclonal antibody, PBS Only

FOXC1 Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

1F4E11

Cat no : 66568-1-PBS

Synonyms

FREAC 3, Forkhead-related transcription factor 3, Forkhead-related protein FKHL7, FKHL7, ARA

Validation Data Gallery

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  • Western Blot (WB) analysis of HEK-293 cells using FOXC1 Monoclonal antibody (66568-1-Ig)

    WB analysis of HEK-293 using 66568-1-Ig (same clone as 66568-1-PBS)

    WB result of FOXC1 antibody (66568-1-Ig; 1:10000; incubated at room temperature for 1.5 hours) with sh-Control and sh-FOXC1 transfected HEK-293 cells. This data was developed using the same antibody clone with 66568-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of various lysates using FOXC1 Monoclonal antibody (66568-1-Ig)

    WB analysis using 66568-1-Ig (same clone as 66568-1-PBS)

    Various cells were subjected to SDS PAGE followed by western blot with 66568-1-Ig (FOXC1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66568-1-PBS in a different storage buffer formulation.

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Tested Applications

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

66568-1-PBS targets FOXC1 in WB, Indirect ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen Peptide 相同性解析による交差性が予測される生物種
Full Name forkhead box C1
Calculated molecular weight 57 kDa
Observed molecular weight 70-75 kDa
GenBank accession numberNM_001453
Gene symbol FOXC1
Gene ID (NCBI) 2296
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

FOXC1, also named as FKHL7 and FREAC3, binding of FREAC-3 and FREAC-4 to their cognate sites results in bending of the DNA at an angle of 80-90 degrees. Defects in FOXC1 are the cause of Axenfeld-Rieger syndrome type 3 (RIEG3). Defects in FOXC1 are the cause of iridogoniodysgenesis anomaly (IGDA). Defects in FOXC1 are a cause of Peters anomaly.