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FceR1a Recombinant antibody

FceR1a Uni-rAbTM Recombinant Antibody for WB, ELISA
Cat No. 84662-3-RR
Clone No.241848D1

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

FceRIa, FcERI, Fc-epsilon RI-alpha, FCE1A, Fc epsilon RI alpha

Formulation:  PBS and Azide
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Unconjugated
Size/Concentration: 

-/ -


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保証・サポートについて

テクニカルサポートまたはご購入後1年間の交換/補填対応を承ります。詳細はこちらをご覧ください。


Tested Applications

Positive WB detected inhuman testis tissue

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:2000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

84662-3-RR targets FceR1a in WB, ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen Recombinant protein 相同性解析による交差性が予測される生物種
Full Name Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
Calculated molecular weight30kDa
Observed molecular weight55-65 kDa
GenBank accession numberNM_001387280.1
Gene Symbol FceR1a
Gene ID (NCBI) 2205
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDP12319
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

Fc epsilon Receptor I alpha (FceR1a) is a single-pass type I membrane protein that contains 2 immunoglobulin-like domains. FceR1a forms a tetrameric complex, FceRI, with one beta and two gamma subunits (PMID: 19406478). FceRI is the high-affinity receptor for the Fc region of immunoglobulin E (IgE) (PMID: 1532373). It is expressed on mast cells and basophils and plays a central role in the allergic response (PMID: 2148316). The calculated molecular weight of FceR1a is 30 kDa, the 55- to 70-kDa bands detected by this antibody are probably caused by heterogeneous glycosylation (PMID: 11344350; 12671054).

Protocols

Product Specific Protocols
WB protocol for FceR1a antibody 84662-3-RRDownload protocol
Standard Protocols
Click here to view our Standard Protocols
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