- Featured Product
- KD/KO Validated
Fibulin 5 Monoclonal antibody, PBS Only
Fibulin 5 Monoclonal Antibody for WB, IF/ICC, ELISA
Host / Isotype
Mouse / IgG1
Reactivity
human, mouse, rat, pig
Applications
WB, IF/ICC, ELISA
Conjugate
Unconjugated
CloneNo.
2A5C8
Cat no : 60081-1-PBS
Synonyms
Validation Data Gallery
Tested Applications
Recommended dilution
Application | Dilution |
---|---|
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. |
Product Information
60081-1-PBS targets Fibulin 5 in WB, IF/ICC, ELISA applications and shows reactivity with human, mouse, rat, pig samples.
Tested Reactivity | human, mouse, rat, pig |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Immunogen | Fibulin 5 fusion protein Ag2859 相同性解析による交差性が予測される生物種 |
Full Name | fibulin 5 |
Calculated molecular weight | 448 aa, 50 kDa |
Observed molecular weight | 65 kDa |
GenBank accession number | BC022280 |
Gene symbol | Fibulin 5 |
Gene ID (NCBI) | 10516 |
RRID | AB_2231920 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS only |
Storage Conditions | Store at -80°C. |
Background Information
Fibulin-5, also known as EVEC and DANCE, is a extracellular matrix glycoprotein, secreted by various cell types such as vascular smooth muscle cells, fibroblasts and endothelial cells. Structurally, Fibulin-5 contains an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. FBLN5 mutations have been described in patients with age-related macular degeneration, as well as being involved in Charcot-Marie-Tooth neuropathies.