Validation Data Gallery
Filter:
Tested Applications
| Positive WB detected in | mouse brain tissue |
| Positive IHC detected in | human gliomas tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:500-1:2000 |
| Immunohistochemistry (IHC) | IHC : 1:50-1:500 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Published Applications
| KD/KO | See 2 publications below |
| WB | See 4 publications below |
| IHC | See 2 publications below |
| IF | See 3 publications below |
Product Information
17903-1-AP targets GAS1 in WB, IF, IHC, ELISA applications and shows reactivity with human, mouse samples.
| Tested Reactivity | human, mouse |
| Cited Reactivity | human, mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | GAS1 fusion protein Ag12275 相同性解析による交差性が予測される生物種 |
| Full Name | growth arrest-specific 1 |
| Calculated molecular weight | 345 aa, 36 kDa |
| Observed molecular weight | 36 kDa |
| GenBank accession number | BC074908 |
| Gene Symbol | GAS1 |
| Gene ID (NCBI) | 2619 |
| RRID | AB_2878463 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | P54826 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
GAS1 is involved in growth suppression. It is an integral plasma membrane protein whose expression is linked to growth arrest. It can be used as a novel therapeutic candidate for gastric cancer.
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for GAS1 antibody 17903-1-AP | Download protocol |
| IHC protocol for GAS1 antibody 17903-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
Publications
| Species | Application | Title |
|---|---|---|
Cancer Commun (Lond) Bifidobacterium adolescentis orchestrates CD143+ cancer-associated fibroblasts to suppress colorectal tumorigenesis by Wnt signaling-regulated GAS1 | ||
Sci Rep Gene-Related Response of Basal Cell Carcinoma to Biologic Treatment with Vismodegib. | ||
Exp Ther Med microRNA-mediated GAS1 downregulation promotes the proliferation of synovial fibroblasts by PI3K-Akt signaling in osteoarthritis.
| ||
FASEB Bioadv Critical cysteines in the functional interaction of adenylyl cyclase isoform 6 with Gαs. | ||
Int J Med Sci GAS1 Promotes Ferroptosis of Liver Cells in Acetaminophen-Induced Acute Liver Failure
|