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Target

Host

Species Reactivity

Species Reactivity

Conjugate

Conjugate

GBA2 Polyclonal antibody

GBA2 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 17164-1-AP

Synonyms

AD035, Beta glucocerebrosidase 2, Beta glucosidase 2, GBA2, Glucosylceramidase 2, KIAA1605, NLGase

Validation Data Gallery

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  • Western Blot (WB) analysis of various lysates using GBA2 Polyclonal antibody (17164-1-AP)

    WB analysis using 17164-1-AP

    Human placenta tissue were subjected to SDS PAGE followed by western blot with 17164-1-AP (GBA2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

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Tested Applications

Positive WB detected inhuman placenta tissue

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:2000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

17164-1-AP targets GBA2 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen GBA2 fusion protein Ag10606 相同性解析による交差性が予測される生物種
Full Name glucosidase, beta (bile acid) 2
Calculated molecular weight 927 aa, 105 kDa
Observed molecular weight 105 kDa
GenBank accession numberBC011363
Gene symbol GBA2
Gene ID (NCBI) 57704
RRIDAB_2109077
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

GBA2(Non-lysosomal glucosylceramidase) is also named as KIAA1605,NLGase and belongs to the non-lysosomal glucosylceramidase family.It catalyzes the conversion of glucosylceramide to free glucose and ceramide and is involved in sphingomyelin generation and prevention of glycolipid accumulation.GBA2 contains a putative membrane-spanning domain and 2 potential N-glycosylation sites. However, glycosidase treatment indicated that GBA2 is not a glycoprotein(PMID:11489889).It has 3 isoforms produced by alternative splicing.

Protocols

Product Specific Protocols
WB protocol for GBA2 antibody 17164-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols