Validation Data Gallery
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
68340-1-PBS targets GDAP1L1 in WB, Indirect ELISA applications and shows reactivity with Human, mouse, rat, pig, rabbit samples.
| Tested Reactivity | Human, mouse, rat, pig, rabbit |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | GDAP1L1 fusion protein Ag27717 相同性解析による交差性が予測される生物種 |
| Full Name | ganglioside-induced differentiation-associated protein 1-like 1 |
| Calculated molecular weight | 367 aa, 42 kDa |
| Observed molecular weight | 38-40 kDa |
| GenBank accession number | BC009014 |
| Gene Symbol | GDAP1L1 |
| Gene ID (NCBI) | 78997 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | Q96MZ0 |
| Storage Buffer | PBS only , pH 7.3 |
| Storage Conditions | Store at -80°C. |
Background Information
Ganglioside-induced differentiation-associated protein 1-like 1 (GDAP1L1) belongs to GST superfamily. Owing to its central role in mitochondrial fission, GDAP1L1 is a homologue of GDAP1 implicated in cellular processes, such as cell death, autophagy, aging, and immune response regulation (PMID:32230997). GDAP1L1, a fission factor controlling mitochondrial fission, induces fission upon translocation from the cytosol to mitochondria in response to stress condition (PMID:34638757). Furthermore, the activity of GDAP1L1 is dependent on Drp1. GDAP1, a paralog of GDAP1L1, evokes mitochondrial fragmentation only in the presence of Drp1 in HeLa cells (PMID:19782751).