Validation Data Gallery
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Tested Applications
| Positive WB detected in | HepG2 cells, L02 cells, human urine |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:500-1:3000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Product Information
83392-3-RR targets GGTLC1 in WB, ELISA applications and shows reactivity with Human samples.
| Tested Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Immunogen | GGTLC1 fusion protein Ag11592 相同性解析による交差性が予測される生物種 |
| Full Name | gamma-glutamyltransferase light chain 1 |
| Calculated molecular weight | 225 aa, 24 kDa |
| Observed molecular weight | 20-24 kDa |
| GenBank accession number | BC040904 |
| Gene Symbol | GGTLC1 |
| Gene ID (NCBI) | 92086 |
| RRID | AB_3671046 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | Q9BX51 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
Gamma-glutamyltransferase light chain 1 (GGTLC1), initially named GGTL6, then GGTLA4, and later GGTLC1 in 2008, is a member of the gamma-glutamyl transferase (GGT) family. The most ubiquitously expressed human GGT gene, GGT1, encodes a single transmembrane polypeptide that is post-translationally processed to form a heavy and a light chain. Knockdown of GGTLC1 in Endometrial cancer (EC) cells was shown to induce G0/G1 phase arrest and apoptosis, underscoring the significance of GGTLC1 as a key regulator of these cellular processes in EC (PMID: 38841516).
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for GGTLC1 antibody 83392-3-RR | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |