GLUD1 Monoclonal antibody, PBS Only
GLUD1 Monoclonal Antibody for WB, IHC, IF-P, Indirect ELISA
Host / Isotype
Mouse / IgG2b
Reactivity
Human, Mouse, Rat
Applications
WB, IHC, IF-P, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
4G10D3
Cat no : 67026-1-PBS
Synonyms
Validation Data Gallery
Tested Applications
Recommended dilution
Application | Dilution |
---|---|
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. |
Product Information
67026-1-PBS targets GLUD1 in WB, IHC, IF-P, Indirect ELISA applications and shows reactivity with Human, Mouse, Rat samples.
Tested Reactivity | Human, Mouse, Rat |
Host / Isotype | Mouse / IgG2b |
Class | Monoclonal |
Type | Antibody |
Immunogen | GLUD1 fusion protein Ag6179 相同性解析による交差性が予測される生物種 |
Full Name | glutamate dehydrogenase 1 |
Calculated molecular weight | 61 kDa |
Observed molecular weight | 45-55 kDa |
GenBank accession number | BC040132 |
Gene symbol | GLUD1 |
Gene ID (NCBI) | 2746 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
Human glutamate dehydrogenase (GDH), an enzyme central to the metabolism of glutamate, is known to exist in housekeeping and nerve tissue-specific isoforms encoded by the GLUD1 and GLUD2 genes, respectively. It catalyses the reversible inter-conversion of glutamate to alpha-ketoglutarate and ammonia, thus interconnecting amino acid and carbohydrate metabolism. GLUD1 might contribute to the formation of specific synapses in the hippocampus such as those formed by the projecting neurons of the entorhinal cortex(PMID: 22138648). GLUD1 has a calculated molecular mass of 61 kDa and an apparent molecular mass of 45-55 kDa with the 53aa transit peptide removed.