GNAS Monoclonal antibody, PBS Only
GNAS Monoclonal Antibody for WB, IHC, IF/ICC, IF-P, Indirect ELISA
Host / Isotype
Mouse / IgG2b
Reactivity
human, pig
Applications
WB, IHC, IF/ICC, IF-P, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
1A9C10
Cat no : 66253-1-PBS
Synonyms
Validation Data Gallery
Tested Applications
Recommended dilution
Application | Dilution |
---|---|
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. |
Product Information
66253-1-PBS targets GNAS in WB, IHC, IF/ICC, IF-P, Indirect ELISA applications and shows reactivity with human, pig samples.
Tested Reactivity | human, pig |
Host / Isotype | Mouse / IgG2b |
Class | Monoclonal |
Type | Antibody |
Immunogen | GNAS fusion protein Ag20530 相同性解析による交差性が予測される生物種 |
Full Name | GNAS complex locus |
Calculated molecular weight | 45 kDa |
Observed molecular weight | 46 kDa |
GenBank accession number | BC002722 |
Gene symbol | GNAS |
Gene ID (NCBI) | 2778 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
Guanine nucleotide binding protein (G protein), alpha stimulating activity polypeptide 1 (GNAS1) is the ubiquitously expressed heterotrimeric G protein that couples receptors to the effector enzyme adenylyl cyclase and is required for receptor-stimulated intracellular cAMP generation. Mutations of Gs(alpha) residues involved in the GTPase reaction that lead to constitutive activation are present in endocrine tumors, fibrous dysplasia of bone, and McCune-Albright syndrome. The molecular weight of Gs(alpha) protein is about 46 kDa.