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Validation Data Gallery

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  • Immunohistochemistry (IHC) staining of mouse brain tissue using GPR137 Polyclonal antibody (11929-1-AP)

    IHC staining of mouse brain using 11929-1-AP (same clone as 11929-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 11929-1-AP (GPR137 Antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11929-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of mouse brain tissue using GPR137 Polyclonal antibody (11929-1-AP)

    IHC staining of mouse brain using 11929-1-AP (same clone as 11929-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 11929-1-AP (GPR137 Antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11929-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of mouse brain tissue using GPR137 Polyclonal antibody (11929-1-AP)

    IHC staining of mouse brain using 11929-1-AP (same clone as 11929-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 11929-1-AP (GPR137 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11929-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human gliomas tissue using GPR137 Polyclonal antibody (11929-1-AP)

    IHC staining of human gliomas using 11929-1-AP (same clone as 11929-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human gliomas using 11929-1-AP (GPR137 antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 11929-1-PBS in a different storage buffer formulation.

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  • Featured Product
  • KD/KO Validated

GPR137 Polyclonal antibody, PBS Only

GPR137 Polyclonal Antibody for IHC, Indirect ELISA
Cat No. 11929-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

IHC, Indirect ELISA

Synonyms

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

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Tested Applications

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

11929-1-PBS targets GPR137 in IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen GPR137 fusion protein Ag2611 相同性解析による交差性が予測される生物種
Full Name G protein-coupled receptor 137
Calculated molecular weight 396 aa, 44 kDa
GenBank accession numberBC033920
Gene Symbol GPR137
Gene ID (NCBI) 56834
RRIDAB_10694423
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ96N19
Storage Buffer PBS only , pH 7.3
Storage ConditionsStore at -80°C.

Background Information

G protein-coupled receptors (GPRs) are highly related to oncogenesis and cancer metastasis. G protein-coupled receptor 137 (GPR137) was initially reported as a novel orphan GPR about 10 years ago. GPR137 is ubiquitously expressed in the central nervous system (CNS), mainly in the hippocampus (PMID: 22025619). GPR137 is involved in the progression of human glioma, suggesting GPR137 as a potential oncogene of glioma cells (PMID: 24870220). Recent study shows that GPR137 plays an important role in colon cancer cell proliferation (PMID: 25301753).