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Target

Host

Species Reactivity

Species Reactivity

Conjugate

Conjugate

GPR17 Polyclonal antibody

GPR17 Polyclonal Antibody for IF-P, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

IF-P, ELISA

Conjugate

Unconjugated

Cat no : 13416-1-AP

Synonyms

UDP/CysLT receptor, R12, P2Y-like receptor, P2Y like receptor, G-protein coupled receptor 17

Validation Data Gallery

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  • Immunofluorescence (IF) / fluorescent staining of mouse cerebellum tissue using GPR17 Polyclonal antibody (13416-1-AP)

    IF Staining of mouse cerebellum using 13416-1-AP

    Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded mouse cerebellum tissue using GPR17 antibody (13416-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

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Tested Applications

Positive IF-P detected inmouse cerebellum tissue

Recommended dilution

ApplicationDilution
Immunofluorescence (IF)-PIF-P : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

13416-1-AP targets GPR17 in IF-P, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen GPR17 fusion protein Ag4106 相同性解析による交差性が予測される生物種
Full Name G protein-coupled receptor 17
Calculated molecular weight 367 aa, 41 kDa
Observed molecular weight 50 kDa
GenBank accession numberBC031653
Gene symbol GPR17
Gene ID (NCBI) 2840
RRIDAB_2279341
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

GPR17 is a G protein-coupled receptor (GPCR) that plays a significant role in various physiological processes, particularly in the central nervous system (CNS). GPR17 is considered a modulator of CNS myelination and is involved in reconstructing and repairing demyelinating plaques caused by ongoing inflammatory processes, such as in multiple sclerosis (MS). It is present in nerve cells and precursor oligodendrocyte cells, playing a role in the differentiation and maturation of oligodendrocytes (PMID: 32182666). GPR17 is a multifaceted GPCR with implications in immune regulation, glucose metabolism, neurodegenerative diseases, and potentially in treating anxiety disorders.

Protocols

Product Specific Protocols
IF protocol for GPR17 antibody 13416-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols