Validation Data Gallery
Tested Applications
Recommended dilution
Application | Dilution |
---|---|
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. |
Product Information
67763-1-PBS targets GPX4 in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse, rat, pig, rabbit, chicken, zebrafish, hamster, dog samples.
Tested Reactivity | human, mouse, rat, pig, rabbit, chicken, zebrafish, hamster, dog |
Host / Isotype | Mouse / IgG2b |
Class | Monoclonal |
Type | Antibody |
Immunogen | GPX4 fusion protein Ag30650 相同性解析による交差性が予測される生物種 |
Full Name | glutathione peroxidase 4 (phospholipid hydroperoxidase) |
Observed molecular weight | 20-23 kDa |
GenBank accession number | BC021567 |
Gene Symbol | GPX4 |
Gene ID (NCBI) | 2879 |
RRID | AB_2909469 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | P36969 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
GPX4 (Phospholipid hydroperoxide glutathione peroxidase, mitochondrial) protects cells against membrane lipid peroxidation and cell death. Required for normal sperm development and male fertility.It has two isforms about 20KDa and 22KDa, respectively. GPX4 is a monomer,but it has a tendency to form higher mass oligomers (PMID:17630701). It presents primarily in testis.