- Featured Product
- KD/KO Validated
GRK2 Polyclonal antibody, PBS Only
GRK2 Polyclonal Antibody for WB, IHC, FC (Intra), IP, Indirect ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human
Applications
WB, IHC, FC (Intra), IP, Indirect ELISA
Conjugate
Unconjugated
Cat no : 13990-1-PBS
Synonyms
Validation Data Gallery
Tested Applications
Recommended dilution
Application | Dilution |
---|---|
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. |
Product Information
13990-1-PBS targets GRK2 in WB, IHC, FC (Intra), IP, Indirect ELISA applications and shows reactivity with human samples.
Tested Reactivity | human |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | GRK2 fusion protein Ag5071 相同性解析による交差性が予測される生物種 |
Full Name | adrenergic, beta, receptor kinase 1 |
Calculated molecular weight | 689 aa, 80 kDa |
Observed molecular weight | 80 kDa |
GenBank accession number | BC037963 |
Gene symbol | ADRBK1 |
Gene ID (NCBI) | 156 |
RRID | AB_2225833 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
GRK2 (G-protein coupled receptor kinase 2) is also named as ADRBK1 (Beta-adrenergic receptor kinase 1), BARK, and BARK1. G-protein-coupled receptors (GPCRs) transmit extracellular signals across the cell membrane. GPCR kinases (GRKs) desensitize GPCR signals in the cell membrane. GRK2 translocation from the cytoplasm to the cell membrane in response to extracellular signals is critical to the function of the protein, where GRK phosphorylation is an important component of its translocation to the membrane.(PMID:27412951)