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Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
67272-1-PBS targets Granzyme K in IHC, IF-P, ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | Granzyme K fusion protein Ag27297 相同性解析による交差性が予測される生物種 |
| Full Name | granzyme K (granzyme 3; NK tryptase II) |
| Calculated molecular weight | 29 kDa |
| GenBank accession number | BC035802 |
| Gene Symbol | GZMK |
| Gene ID (NCBI) | 3003 |
| RRID | AB_2882541 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | P49863 |
| Storage Buffer | PBS Only |
| Storage Conditions | Store at -80°C. |
Background Information
Granzymes are a family of serine proteases stored in granules inside cytotoxic cells of the immune system. There are five human granzymes (granzyme A (GrA), GrB, GrH, GrK and GrM) currently identified, whereas mice have ten known granzymes (GrA-G, GrK, GrM and GrN) (PMID:14499263). Human GrK was first discovered in 1988 after purification from human peripheral blood mononuclear cells. GrK is expressed by cytotoxic T lymphocytes, natural killer T cells (NKT), γδ T cells and CD56bright+ NK cells.