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KIM-1/HAVCR1 Polyclonal antibody

HAVCR1 Polyclonal Antibody for ELISA
Cat No. 26420-1-AP

Host / Isotype

Rabbit / IgG

Reactivity

human and More (1)

Applications

IHC, ELISA

CD365, HAVCR, HAVCR 1, HAVCR1, Kidney injury molecule 1, KIM 1, KIM1, T cell membrane protein 1, TIM, TIM 1, TIM1, TIMD 1, TIMD1

Formulation:  PBS and Azide
PBS and Azide
Conjugate:  Unconjugated
Size/Concentration: 

-/ -


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国内在庫・納期について

約2万点のプロテインテック製品をコスモバイオ社物流センター(国内)に在庫しています。国内在庫の有無はコスモバイオ社ホームページの「品番検索」でカタログ番号を検索して確認できます。


保証・サポートについて

テクニカルサポートまたはご購入後1年間の交換/補填対応を承ります。詳細はこちらをご覧ください。


Tested Applications

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

26420-1-AP targets HAVCR1 in IHC, ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Cited Reactivitymouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen HAVCR1 fusion protein Ag23888 相同性解析による交差性が予測される生物種
Full Name hepatitis A virus cellular receptor 1
Calculated molecular weight 359 aa, 39 kDa
GenBank accession numberBC013325
Gene Symbol HAVCR1
Gene ID (NCBI) 26762
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ96D42
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

Hepatitis A virus cellular receptor 1 (HAVCR1, also known as TIM-1, KIM-1 or CD365) is a class I integral membrane glycoprotein, with an ectodomain containing Ig-like domain and a mucin domain. HAVCR1 acts as a membrane receptor for hepatitis A virus (HHAV) (PMID: 9658108; 8861957). HAVCR1 provides a costimulatory signal for T cell activation and inhibits the development of peripheral tolerance (PMID: 16284246; 15793575). HAVCR1 may be involved in the regulation of asthma and allergic diseases (PMID: 14534576). It has been reported that HAVCR1 is shed into urine after acute kidney damage and is a marker of renal tubular injury (PMID: 14600030).

Publications

SpeciesApplicationTitle
mouseIHC,IF

Drug Deliv

Sialic acid-modified solid lipid nanoparticles as vascular endothelium-targeting carriers for ischemia-reperfusion-induced acute renal injury.

Authors - Jing-Bo Hu
mouseIHC

Redox Biol

Silibinin attenuates ferroptosis in acute kidney injury by targeting FTH1

Authors - Yijian Deng
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