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ICOSLG/B7-H2/CD275 Monoclonal antibody, PBS Only

ICOSLG/B7-H2/CD275 Monoclonal Antibody for WB, Indirect ELISA
Cat No. 67003-1-PBS
Clone No.2G1F8

Host / Isotype

Mouse / IgG2a

Reactivity

Human

Applications

WB, Indirect ELISA

B7H2, ICOSLG, B7RP1, B7-related protein 1, B7-like protein Gl50

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -


ご購入について

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国内在庫・納期について

約2万点のプロテインテック製品をコスモバイオ社物流センター(国内)に在庫しています。国内在庫の有無はコスモバイオ社ホームページの「品番検索」でカタログ番号を検索して確認できます。


保証・サポートについて

テクニカルサポートまたはご購入後1年間の交換/補填対応を承ります。詳細はこちらをご覧ください。


Tested Applications

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

67003-1-PBS targets ICOSLG/B7-H2/CD275 in WB, Indirect ELISA applications and shows reactivity with Human samples.

Tested Reactivity Human
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Immunogen ICOSLG/B7-H2/CD275 fusion protein Ag6799 相同性解析による交差性が予測される生物種
Full Name inducible T-cell co-stimulator ligand
Calculated molecular weight 33 kDa, 34 kDa
Observed molecular weight 60-65 kDa, 28-35 kDa
GenBank accession numberBC064637
Gene Symbol ICOSLG
Gene ID (NCBI) 23308
RRIDAB_2882320
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDO75144
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

ICOSLG, also known as B7H2 or GL50, is a type I transmembrane glycoprotein belonging to the B7 ligand family. ICOSLG is extensively expressed on professional antigen-presenting cells including B cells, macrophages, and dendritic cells, as well as non-lymphoid cells including mesenchymal stem cells, endothelial cells, fibroblasts, and tumor cells (PMID: 33756276; 35800767). It is a specific ligand for the T-cell-specific cell surface receptor ICOS and acts as a co-stimulatory molecule (PMID: 11023515; 11007762). The interaction of ICOSLG and ICOS plays important roles in the activation, proliferation, differentiation, and cytokine production of T cells as well as in the antibody secretion from B cells during secondary immune responses (PMID: 21851236).

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